Supplementary Figures from Nuclear Localized LSR: A Novel Regulator of Breast Cancer Behavior and Tumorigenesis

S1. QPCR analysis of luminal progenitor and cancer stem cell genes. Primers were designed against the indicated genes. S2. Representative Z-stack projections of MCF7 breast cancer and MCF10AI breast epithelial cells generated from deconvolved slices using the maximum intensity criteria. S3. Ingenuity Pathway Analysis identification of the top biological functions and disorders associated with LSR target genes. S4. Top network generated via Path Designer of Ingenuity Pathway Analysis with LSR target genes. S5. ChIP-QPCR analysis of LSR target genes. S6. LSR expression in breast tumors stratified by menopause status. S7. Analysis of LSR expression in breast tumors. S8. Integrative Genomics Viewer snapshot image of RNA-seq data from MCF7, SUM149, SUM!59 and MDA-MB231 breast cancer cell lines. S9. Evolutionary conservation of LSR. S10. Predicted phosphorylation sites of full-length LSR. S11. Subcellular localization of LSR protein upon treatment with posttranslation modification pharmacologicals. S12. Localization of LSR binding sites on chromosomes.