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Venous thromboembolic events in lymphoma patients: Actual relationships between epidemiology, mechanisms, clinical profile and treatment
- Source :
- Blood Reviews. 32:144-158
- Publication Year :
- 2018
- Publisher :
- Elsevier BV, 2018.
-
Abstract
- Venous thromboembolic events (VTE) are an underestimated health problem in patients with lymphoma. Many factors contribute to the pathogenesis of thromboembolism and the interplay between various mechanisms that provoke VTE is still poorly understood. The identification of parameters that are associated with an increased risk of VTE in lymphoma patients led to the creation of several risk-assessment models. The models that evaluate potential VTE risk in lymphoma patients in particular are quite limited, and have to be validated in larger study populations. Furthermore, the VTE prophylaxis in lymphoma patients is largely underused, despite the incidence of VTE. The lack of adequate guidelines for the prophylaxis and treatment of VTE in lymphoma patients, together with a cautious approach due to an increased risk of bleeding, demands great efforts to ensure the implementation of current knowledge in order to reduce the incidence and complications of VTE in lymphoma patients.
- Subjects :
- medicine.medical_specialty
Lymphoma
030204 cardiovascular system & hematology
Vte prophylaxis
Risk Assessment
03 medical and health sciences
0302 clinical medicine
Risk Factors
hemic and lymphatic diseases
Epidemiology
Humans
Medicine
In patient
cardiovascular diseases
Intensive care medicine
business.industry
Incidence
Incidence (epidemiology)
Venous Thromboembolism
Hematology
equipment and supplies
medicine.disease
Combined Modality Therapy
3. Good health
Treatment Outcome
Increased risk
Oncology
030220 oncology & carcinogenesis
business
Risk assessment
Biomarkers
Subjects
Details
- ISSN :
- 0268960X
- Volume :
- 32
- Database :
- OpenAIRE
- Journal :
- Blood Reviews
- Accession number :
- edsair.doi.dedup.....cad8d1713049c24ffc08d87aee47f5cc
- Full Text :
- https://doi.org/10.1016/j.blre.2017.10.002