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Intraoperative Dexmedetomidine and Ketamine Infusions in an Enhanced Recovery After Thoracic Surgery Program: A Propensity Score Matched Analysis

Authors :
Reza J. Mehran
David C. Rice
Ta Charra Woodward
Brittany Kruse
Girish P. Joshi
Wendell H. Williams
Javier Lasala
Carla M Patel
Gabriel E. Mena
Andres Zorrilla-Vaca
Ara A. Vaporciyan
Source :
Journal of Cardiothoracic and Vascular Anesthesia. 36:1064-1072
Publication Year :
2022
Publisher :
Elsevier BV, 2022.

Abstract

OBJECTIVES To assess the impact of intraoperative dexmedetomidine and ketamine on postoperative pain and opioid consumption within an ERAS program in thoracic pulmonary oncologic surgery. DESIGN Retrospective, propensity-score matched analysis SETTING: Enhanced Recovery After Surgery (ERAS) program. PARTICIPANTS Patients undergoing thoracic pulmonary oncologic surgery between March 2016 and April 2020. INTERVENTIONS Continuous infusion of dexmedetomidine and ketamine. MEASUREMENTS & MAIN RESULTS The authors initially analyzed data of 1,630 patients undergoing thoracic pulmonary oncologic surgery within their ERAS program. In total, 117 matched pairs were included in this analysis. Patients in the intraoperative dexmedetomidine + ketamine group were more likely to be opioid-free (76.6% vs 60.9%, P

Details

ISSN :
10530770
Volume :
36
Database :
OpenAIRE
Journal :
Journal of Cardiothoracic and Vascular Anesthesia
Accession number :
edsair.doi.dedup.....cab9bfbaba8d63a17e881630f509b6ce
Full Text :
https://doi.org/10.1053/j.jvca.2021.09.038