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Identification of shyc, a novel gene expressed in the murine developing and adult nervous system
- Source :
- Neuroscience Letters. 252:69-71
- Publication Year :
- 1998
- Publisher :
- Elsevier BV, 1998.
-
Abstract
- The embryonal carcinoma cell line P19 responds to treatment with retinoid acid by differentiation into neuronal cell types [2]. Using radioactively labeled cDNA derived from differentiating P19 cells we screened an adult mouse brain cDNA library and isolated a gene named shyc for selective hybridizing clone. The encoded protein did not reveal homology to any known protein. We used in situ hybridization on mouse embryonic and adult brain sections to study shyc expression. The developing and embryonic nervous system showed the most prominent hybridization signals. In the adult brain the olfactory pathway was marked by shyc expression.
- Subjects :
- Nervous system
Embryonal Carcinoma Stem Cells
Molecular Sequence Data
Central nervous system
Nerve Tissue Proteins
In situ hybridization
Biology
Embryonal carcinoma
Mice
Complementary DNA
Gene expression
medicine
Animals
Amino Acid Sequence
In Situ Hybridization
Adaptor Proteins, Signal Transducing
Brain Chemistry
cDNA library
General Neuroscience
Age Factors
Brain
Gene Expression Regulation, Developmental
medicine.disease
Cell biology
medicine.anatomical_structure
P19 cell
Immunology
Neoplastic Stem Cells
Subjects
Details
- ISSN :
- 03043940
- Volume :
- 252
- Database :
- OpenAIRE
- Journal :
- Neuroscience Letters
- Accession number :
- edsair.doi.dedup.....ca9bb663d045710248bbc7851c68f22b