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Insulin Autoimmune Syndrome in a Health Supplement User: The Effectiveness of Cornstarch Therapy for Treating Hypoglycemia
- Source :
- Internal Medicine. 52:369-372
- Publication Year :
- 2013
- Publisher :
- Japanese Society of Internal Medicine, 2013.
-
Abstract
- A 70-year-old woman with no history of diabetes was admitted to the hospital for the management of hypoglycemia. Her fasting plasma glucose level was 54 mg/dL with an extremely high serum immunoreactive insulin level (1,210 μU/mL). She had high titers of anti-insulin antibodies and exhibited the DRB1*0406 genotype for HLA-DR4, leading to a diagnosis of insulin autoimmune syndrome. She had been taking several health preparations for approximately 10 years; however, all were thiol group-free. Due to frequent episodes of nocturnal hypoglycemia, the health preparations were discontinued and the patient was treated with cornstarch. This protocol successfully ameliorated the hypoglycemic episodes and normalized the patient's laboratory and serological test results.
- Subjects :
- medicine.medical_specialty
Insulin Antibodies
Hypoglycemic episodes
Hypoglycemia
Nocturnal hypoglycemia
Gastroenterology
Autoimmune Diseases
Serology
Methionine
Diabetes mellitus
Internal medicine
Insulin autoimmune syndrome
HLA-DR4 Antigen
Internal Medicine
medicine
Humans
Insulin
Aged
Autoantibodies
Immunoreactive insulin
biology
business.industry
Starch
Syndrome
General Medicine
medicine.disease
Endocrinology
Dietary Supplements
biology.protein
Female
Antibody
business
HLA-DRB1 Chains
Subjects
Details
- ISSN :
- 13497235 and 09182918
- Volume :
- 52
- Database :
- OpenAIRE
- Journal :
- Internal Medicine
- Accession number :
- edsair.doi.dedup.....ca921ff814a3fdf90ec539b6f8c1792e