Metabolic studies on N-methylpyridinium-2-aldoxime. III. Experiments with the 14C-labelled compound

N-methylpyridinium-2-aldoxime iodide (PAM), labelled with 14 C on the methyl group, was injected into rats and the excretion of the isotope in the urine was followed. Most of the radioactivity was excreted as unchanged PAM, but paper chromatography also demonstrated the formation of a number of metabolites, among which N-methylpyridinium-2-nitrile, N-methylpyridinium-2-carboxylic acid (homarine) and N-methyl-2-pyridone were identified.