Rhodium-catalyzed carbonylative coupling of alkyl halides with thiols: a radical process faster than easier nucleophilic substitution

Authors :: Angelika Brückner
Jabor Rabeah
Han-Jun Ai
Xiao-Feng Wu
Source :: Chemical Communications. 57:1466-1469
Publication Year :: 2021
Publisher :: Royal Society of Chemistry (RSC), 2021.
Abstract: How to make a carbonylative coupling faster than the easier nucleophilic substitution? In this communication, a rhodium-catalyzed radical-based carbonylative coupling of alkyl halides with thiolphenols has been realized. Thioesters were isolated in good yields in general.

Subjects :: Coupling
chemistry.chemical_classification
Metals and Alloys
Halide
chemistry.chemical_element
General Chemistry
Medicinal chemistry
Catalysis
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Rhodium
chemistry
Materials Chemistry
Ceramics and Composites
Nucleophilic substitution
lipids (amino acids, peptides, and proteins)
Alkyl

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