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The Virtual Family—development of surface-based anatomical models of two adults and two children for dosimetric simulations

Authors :
Joshua Guag
Jianxiang Shen
M. Oberle
Ji Chen
Marcel Zefferer
Werner Bautz
Anthony Kam
Wolfgang Rascher
Peter Schmitt
Dominik Szczerba
Hans Peter Hollenbach
Berthold Kiefer
Rolf Janka
Katharina Honegger
Eckhart G. Hahn
Niels Kuster
Andreas Christ
Esra Neufeld
Wolfgang Kainz
Source :
Physics in Medicine and Biology. 55:N23-N38
Publication Year :
2009
Publisher :
IOP Publishing, 2009.

Abstract

The objective of this study was to develop anatomically correct whole body human models of an adult male (34 years old), an adult female (26 years old) and two children (an 11-year-old girl and a six-year-old boy) for the optimized evaluation of electromagnetic exposure. These four models are referred to as the Virtual Family. They are based on high resolution magnetic resonance (MR) images of healthy volunteers. More than 80 different tissue types were distinguished during the segmentation. To improve the accuracy and the effectiveness of the segmentation, a novel semi-automated tool was used to analyze and segment the data. All tissues and organs were reconstructed as three-dimensional (3D) unstructured triangulated surface objects, yielding high precision images of individual features of the body. This greatly enhances the meshing flexibility and the accuracy with respect to thin tissue layers and small organs in comparison with the traditional voxel-based representation of anatomical models. Conformal computational techniques were also applied. The techniques and tools developed in this study can be used to more effectively develop future models and further improve the accuracy of the models for various applications. For research purposes, the four models are provided for free to the scientific community.

Details

ISSN :
13616560 and 00319155
Volume :
55
Database :
OpenAIRE
Journal :
Physics in Medicine and Biology
Accession number :
edsair.doi.dedup.....ca4d4adc01f5f281b71e1c57ea95b7d5
Full Text :
https://doi.org/10.1088/0031-9155/55/2/n01