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Assessment of structural lesions, synovitis and bone marrow lesions in erosive hand osteoarthritis on MRI (0.3T) compared to the radiographic anatomical Verbruggen-Veys score
- Source :
- PLoS ONE, PLoS ONE, Public Library of Science, 2020, 15 (6), pp.e0234972. ⟨10.1371/journal.pone.0234972⟩, PLoS ONE, Vol 15, Iss 6, p e0234972 (2020), PLoS ONE, 2020, 15 (6), pp.e0234972. ⟨10.1371/journal.pone.0234972⟩, PLOS ONE
- Publication Year :
- 2020
- Publisher :
- HAL CCSD, 2020.
-
Abstract
- ObjectiveTo evaluate prevalence of structural lesions, synovitis and bone marrow lesions (BMLs) on MRI performed with a 0.3T imaging system in patients with erosive hand osteoarthritis (EHOA) and to compare them to the anatomic radiographic Verbruggen-Veys score (VV).DesignFor this Cross-sectional study, fifty-five EHOA patients were studied with 0.3T contrast-enhanced MRI and radiography (RX) of their dominant hand. Structural lesions were scored according to the OMERACT Hand Osteoarthritis MRI Scoring System as follows: osteophytes and erosions were graded from 0 to 3. On joint destruction lesion synovitis and BMLs were graded from 0 to 1. And on MRI, we evaluated the presence of several structural features: N: normal, O: osteophytic lesions, E: erosive lesions, E/O: osteophytic and erosive lesions and D: joint destruction. RX was scored according to the VV system. Relations between MRI features and VV stages were analysed.ResultsMRI identified more structural lesions than RX (77.3% versus 74.8%) and particularly more erosive lesions (E or E/O) than VV Phase E (33.5% versus 20.2%). E/O and D were mostly found on MRI. Synovitis and BMLs were significantly associated with E/O and D with the following odds ratios (ORs): 8.4 (95% CI 1.8-13.6); OR: 13.7 (95% CI 2.9-21.0); OR: 15.7 (95% CI 3.2-23.5); OR: 38.5 (95% CI 9.5-57.0), respectively.ConclusionMRI 0.3T appears completely relevant for EHOA lesion analysis. First, MRI shows more erosive lesions than RX in EHOA; second, it allows for the analysis of synovitis and BMLs to be associated with more specific structural MRI features (E/O and D).
- Subjects :
- Male
Physiology
[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging
Image Processing
FEATURES
Radiography
Synthesis Phase
Arthritis
PROGRESSION
Osteoarthritis
Pathology and Laboratory Medicine
Severity of Illness Index
RECOMMENDATIONS
Diagnostic Radiology
0302 clinical medicine
Skeletal Joints
Bone Marrow
Immune Physiology
Medicine and Health Sciences
Cell Cycle and Cell Division
Prospective Studies
030212 general & internal medicine
Prospective cohort study
Musculoskeletal System
Randomized Controlled Trials as Topic
ASSOCIATIONS
[SDV.MHEP.RSOA] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system
Synovitis
Multidisciplinary
medicine.diagnostic_test
Radiology and Imaging
Drugs
Middle Aged
Magnetic Resonance Imaging
RADIOLOGICAL ASSESSMENT
medicine.anatomical_structure
[SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system
Cell Processes
RELIABILITY
Engineering and Technology
Medicine
Female
Anatomy
ARTHRITIS
SENSITIVITY
medicine.symptom
Research Article
Imaging Techniques
Hand Joints
Science
Immunology
Research and Analysis Methods
Lesion
03 medical and health sciences
Signs and Symptoms
Rheumatology
Diagnostic Medicine
MANAGEMENT
medicine
Humans
Aged
Pharmacology
030203 arthritis & rheumatology
business.industry
Biology and Life Sciences
Magnetic resonance imaging
Cell Biology
medicine.disease
Methotrexate
Cross-Sectional Studies
[SDV.IB.IMA] Life Sciences [q-bio]/Bioengineering/Imaging
Immune System
Signal Processing
Lesions
Bone marrow
business
Nuclear medicine
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Database :
- OpenAIRE
- Journal :
- PLoS ONE, PLoS ONE, Public Library of Science, 2020, 15 (6), pp.e0234972. ⟨10.1371/journal.pone.0234972⟩, PLoS ONE, Vol 15, Iss 6, p e0234972 (2020), PLoS ONE, 2020, 15 (6), pp.e0234972. ⟨10.1371/journal.pone.0234972⟩, PLOS ONE
- Accession number :
- edsair.doi.dedup.....c9bd911445684df944f7f5b20426b6c2