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Purpura with Ulcerative Skin Lesions and Mixed Cryoglobulinemia in a Quiescent Hepatitis B Virus Carrier
- Source :
- Internal Medicine. 53:115-119
- Publication Year :
- 2014
- Publisher :
- Japanese Society of Internal Medicine, 2014.
-
Abstract
- Mixed cryoglobulinemia is occasionally seen in patients with hepatitis B virus (HBV) infection. This report presents the case of a quiescent HBV carrier who had type II mixed cryoglobulinemia, protracted purpura, ulcerative skin lesions and advanced chronic kidney disease. The cutaneous manifestations of the patient improved along with a decrease in the serum cryoglobulin and HBV-deoxyribonucleic acid levels following the initiation of oral entecavir in combination with plasmapheresis. However, the patient ultimately required prednisolone due to the limited benefits of these treatments. We also discuss various concerns regarding steroid treatment in patients with mixed cryoglobulinemia complicated by HBV infection.
- Subjects :
- Guanine
Prednisolone
medicine.medical_treatment
medicine.disease_cause
Antiviral Agents
Hepatitis B Antigens
Hepatitis B, Chronic
Cryoglobulin
hemic and lymphatic diseases
Skin Ulcer
Internal Medicine
medicine
Humans
Hepatitis B Antibodies
Renal Insufficiency, Chronic
Cryoglobulins
Purpura
Aged
Hepatitis B virus
business.industry
Plasmapheresis
General Medicine
Entecavir
Hepatitis B
medicine.disease
Combined Modality Therapy
digestive system diseases
Cryoglobulinemia
DNA, Viral
Immunology
Female
medicine.symptom
business
medicine.drug
Kidney disease
Subjects
Details
- ISSN :
- 13497235 and 09182918
- Volume :
- 53
- Database :
- OpenAIRE
- Journal :
- Internal Medicine
- Accession number :
- edsair.doi.dedup.....c9aa6933302f43bbbc7ea7a9f3e71144