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Docetaxel-induced hand and foot syndrome in a patient with metastatic breast carcinoma
- Source :
- Indian Journal of Dermatology, Vol 58, Iss 5, Pp 380-382 (2013), Indian Journal of Dermatology
- Publication Year :
- 2013
- Publisher :
- Wolters Kluwer Medknow Publications, 2013.
-
Abstract
- Hand and foot syndrome (HFS) is a well-known complication of chemotherapeutic drugs given in a dose-dense manner. Our patient was a 52-year-old female with metastatic breast carcinoma on salvage chemotherapy regimen with docetaxel at a dose of 60 mg/m(2). The patient had grade 3 HFS characterized by symmetrical, tender, and erythematous skin lesions over the palms and soles associated with dysesthesia necessitating interruption of treatment. She developed this syndrome at a much lower dose than previously described due to her altered hepatic function. An insight regarding this unique distressing side-effect and assessment of various contributing factors would help us identify and treat the patient at the earliest.
- Subjects :
- medicine.medical_specialty
Hand and foot syndrome
Dysesthesia
business.industry
Salvage treatment
palmar - plantar erythrodysesthesia
Case Report
Dermatology
Metastatic Breast Carcinoma
lcsh:RL1-803
Regimen
Docetaxel
medicine
lcsh:Dermatology
medicine.symptom
docetaxel-induced acral erythema
Complication
Skin lesion
business
Foot (unit)
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 19983611 and 00195154
- Volume :
- 58
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Indian Journal of Dermatology
- Accession number :
- edsair.doi.dedup.....c99b03284171e7869ece403505673591