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Erratum: BRaf signaling principles unveiled by large-scale human mutation analysis with a rapid lentivirus-based gene replacement method
- Source :
- Genesdevelopment. 31(8)
- Publication Year :
- 2017
-
Abstract
- Here, Lim et al. present a fast cost-effective lentivirus-based rapid gene replacement method to interrogate the physiopathology of BRaf and ∼50 disease-linked BRaf mutants, including all CFC-linked mutants. This study establishes the first efficient procedure that permits large-scale functional analysis of human disease-linked mutations essential for precision medicine.
- Subjects :
- Genetics
Developmental Biology
Research Paper
Subjects
Details
- ISSN :
- 15495477
- Volume :
- 31
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Genesdevelopment
- Accession number :
- edsair.doi.dedup.....c957a3ba4119ca0d613eedbdf86cf1f1