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Autotransfusion Supported by Erythropoietin Therapy in Transurethral Resection of the Prostate
- Source :
- Scandinavian Journal of Urology and Nephrology. 32:383-387
- Publication Year :
- 1998
- Publisher :
- Informa UK Limited, 1998.
-
Abstract
- We investigated the collection and transfusion of autologous blood after treatment with EPO in 68 BPH patients (including 10 controls) who were scheduled to undergo TUR-P. All patients received oral and/or intravenous iron supplements. Assessments were made based on the preoperative increase in blood hemoglobin levels including autologous blood predonation (deltaHb). The deltaHb in patients undergoing collection of 600 ml of blood were as follows: control group: -0.36 +/- 0.57 g/dl; EPO group, 9 x 3000 units intravenously: 1.15 +/- 0.83 g/dl; EPO group, 6 x 6000 units intravenously: 0.79 +/- 0.80 g/dl; EPO group, 3 x 12,000 units subcutaneously: 1.47 +/- 0.62 g/dl. In patients undergoing collection of 800 ml of blood, the results were as follows: EPO group, 3 x 12,000 units subcutaneously: 1.80 +/- 0.69 g/dl; EPO group, 3 x 24,000 units subcutaneously: 2.03 +/- 0.77 g/dl. All EPO-treated patients successfully underwent surgery using their own blood, and none of them required homologous transfusion. The increase of Hb was greater in the patients treated with EPO than in controls, allowing safe preoperative blood collection even in elderly patients. In patients with relatively severe BPH, homologous transfusion could be avoided and surgery was performed safely.
- Subjects :
- Male
Resuscitation
Urology
medicine.medical_treatment
Prostatic Hyperplasia
Blood cell
Blood Transfusion, Autologous
Hemoglobins
Prostate
medicine
Humans
Erythropoietin
Aged
Transurethral resection of the prostate
Prostatectomy
Chemotherapy
business.industry
Recombinant Proteins
medicine.anatomical_structure
Nephrology
Case-Control Studies
Anesthesia
Erythropoietin therapy
business
medicine.drug
Autotransfusion
Subjects
Details
- ISSN :
- 16512065 and 00365599
- Volume :
- 32
- Database :
- OpenAIRE
- Journal :
- Scandinavian Journal of Urology and Nephrology
- Accession number :
- edsair.doi.dedup.....c94c6fd30271a44496f2b5ab71ebb8e4