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Pathogen spread and globalization: The case of Pestivirus heterogeneity in southern Italy
- Source :
- Research in Veterinary Science. 125:100-112
- Publication Year :
- 2019
- Publisher :
- Elsevier BV, 2019.
-
Abstract
- Pestiviruses are responsible for widespread diseases affecting cattle, pigs and other ruminants, presenting a wide range of clinical manifestations, with significant impact on animal production. Given the recent various reports of a relatively high number of new strains and atypical genomic variants, in the present study, ninety-seven genomic sequences from southern Italy have been evaluated applying the palindromic nucleotide substitutions method, based on 5’-UTR secondary structure alignment and computing genetic distance among strains in the internal ribosome entry site. Sequence analysis revealed a highly heterogeneous virus population, indicating the introduction of virus variants of Bovine viral diarrhea virus and Border disease virus species from foreign countries. The application of different analytical procedures was useful to avoid interpretation difficulties. Circulation of heterogeneous virus populations showed the need for more accurate epidemiological investigations and stringent veterinary controls to protect animal health and welfare.
- Subjects :
- 040301 veterinary sciences
Sequence analysis
Population
Cattle Diseases
Sheep Diseases
Genome, Viral
Biology
Virus
0403 veterinary science
Border disease virus
03 medical and health sciences
Genotype
Animals
education
Pathogen
Phylogeny
030304 developmental biology
Genetics
0303 health sciences
education.field_of_study
Goat Diseases
Sheep
General Veterinary
Goats
Pestivirus
Pestivirus Infections
Border Disease
04 agricultural and veterinary sciences
biology.organism_classification
Italy
RNA, Viral
Cattle
5' Untranslated Regions
Subjects
Details
- ISSN :
- 00345288
- Volume :
- 125
- Database :
- OpenAIRE
- Journal :
- Research in Veterinary Science
- Accession number :
- edsair.doi.dedup.....c921e20bc5b86eb7b743129f6609c2ef