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Clinical Evaluation of BacT/Alert FA Plus and FN Plus Bottles Compared with Standard Bottles
- Source :
- Journal of Clinical Microbiology. 51:4150-4155
- Publication Year :
- 2013
- Publisher :
- American Society for Microbiology, 2013.
-
Abstract
- The performance of the BacT/Alert FA Plus and FN Plus resin bottles was evaluated in comparison with that of standard aerobic (SA) and standard anaerobic (SN) bottles. Twenty milliliters of blood from adult patients was equally distributed into four types of bottles: FA Plus, FN Plus, SA, and SN. The detection of clinically significant organisms and the time to detection (TTD) were monitored for each bottle. Among the 3,103 blood culture sets that were requested, the blood volume of each bottle was over 4 ml in 1,481 sets (47.7%). Among these 1,481 sets, 158 cultures grew in the FA Plus and SA bottles, and 136 grew in the FN Plus and SN bottles. Growth in only one type of bottle was more commonly observed for the FA Plus ( n = 38) than for the SA ( n = 14) ( P = 0.001) bottles and for the FN Plus ( n = 27) than for the SN ( n = 10) ( P = 0.008) bottles. Gram-negative bacilli were more frequently isolated in the resin bottles ( P < 0.05). The skin contamination rate was 1.2% in the resin bottles and the standard bottles. The mean TTD was 11.1 h in the FA Plus bottles versus 13.1 h in the SA bottles ( P < 0.001) and 12.0 h in the FN Plus bottles versus 12.8 h in the SN bottles ( P = 0.083). Clinically significant bacteria, including Gram-negative bacilli, were isolated more frequently from the resin bottles than from the standard bottles. Clinically significant bacteria were detected faster using the aerobic resin bottles than using the standard aerobic bottles. This finding might not be applicable to the standard-practice 10-ml protocol for each bottle because the results from using a smaller volume (5 ml) might be less pronounced.
- Subjects :
- Adult
Male
Microbiology (medical)
medicine.medical_specialty
business.product_category
Adolescent
Bacteremia
Sensitivity and Specificity
Specimen Handling
Young Adult
Bottle
Humans
Medicine
Food science
Aged
Aged, 80 and over
Time to detection
Bacteria
Adult patients
business.industry
Bact alert
Bacteriology
Middle Aged
Surgery
Contamination rate
Blood
Female
business
Clinical evaluation
Subjects
Details
- ISSN :
- 1098660X and 00951137
- Volume :
- 51
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Microbiology
- Accession number :
- edsair.doi.dedup.....c916fa4b15d5b2d75f40dc000d614308
- Full Text :
- https://doi.org/10.1128/jcm.01935-13