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Multi-DNA Adduct and Abasic Site Quantitation In Vivo by Nano-Liquid Chromatography/High-Resolution Orbitrap Tandem Mass Spectrometry: Methodology for Biomonitoring Colorectal DNA Damage

Authors :
Dmitri Konorev
Lihua Yao
Robert. J. Turesky
Source :
Chemical Research in Toxicology. 35:1519-1532
Publication Year :
2022
Publisher :
American Chemical Society (ACS), 2022.

Abstract

Epidemiological and mechanistic studies suggest that processed and red meat consumption and tobacco smoking are associated with colorectal cancer (CRC) risk. Several classes of carcinogens, including

Details

ISSN :
15205010 and 0893228X
Volume :
35
Database :
OpenAIRE
Journal :
Chemical Research in Toxicology
Accession number :
edsair.doi.dedup.....c8fa57a80da8c1ea633254f5882282b8