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Multi-DNA Adduct and Abasic Site Quantitation In Vivo by Nano-Liquid Chromatography/High-Resolution Orbitrap Tandem Mass Spectrometry: Methodology for Biomonitoring Colorectal DNA Damage
- Source :
- Chemical Research in Toxicology. 35:1519-1532
- Publication Year :
- 2022
- Publisher :
- American Chemical Society (ACS), 2022.
-
Abstract
- Epidemiological and mechanistic studies suggest that processed and red meat consumption and tobacco smoking are associated with colorectal cancer (CRC) risk. Several classes of carcinogens, including
- Subjects :
- Lipid Peroxides
Iron
Heme
Hydroxylamines
Toxicology
DNA Adducts
Tandem Mass Spectrometry
Formaldehyde
Tobacco
Animals
Humans
Amines
Polycyclic Aromatic Hydrocarbons
Deoxyguanosine
Reproducibility of Results
DNA
General Medicine
Rats
Pyrimidines
Purines
Carcinogens
Tobacco Smoke Pollution
Colorectal Neoplasms
Biological Monitoring
Chromatography, Liquid
DNA Damage
Nitroso Compounds
Subjects
Details
- ISSN :
- 15205010 and 0893228X
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- Chemical Research in Toxicology
- Accession number :
- edsair.doi.dedup.....c8fa57a80da8c1ea633254f5882282b8