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The impact of urinary incontinence on falls: A systematic review and meta-analysis
- Source :
- PLoS ONE, Vol 16, Iss 5, p e0251711 (2021), PLoS ONE
- Publication Year :
- 2021
- Publisher :
- Public Library of Science (PLoS), 2021.
-
Abstract
- Objective Previous studies on the association between urinary incontinence (UI) and falls have reported conflicting results. We, therefore, aimed to evaluate and clarify this association through a systematic review and meta-analysis of relevant studies. Methods We performed a literature search for relevant studies in databases including PubMed and EMBASE from inception up to December 13, 2020, using several search terms related to UI and falls. Based on the data reported in these studies, we calculated the pooled odds ratios (ORs) for falls and the corresponding 95% confidence intervals (CIs) using the Mantel–Haenszel method. Results This meta-analysis included 38 articles and a total of 230,129 participants. UI was significantly associated with falls (OR, 1.62; 95% CI, 1.45–1.83). Subgroup analyses based on the age and sex of the participants revealed a significant association between UI and falls in older (≥65 years) participants (OR, 1.59; 95% CI, 1.31–1.93), and in both men (OR, 1.88; 95% CI, 1.57–2.25) and women (OR, 1.41; 95% CI, 1.29–1.54). Subgroup analysis based on the definition of falls revealed a significant association between UI and falls (≥1 fall event) (OR, 1.61; 95% CI, 1.42–1.82) and recurrent falls (≥2 fall events) (OR, 1.63; 95% CI, 1.49–1.78). According to the UI type, a significant association between UI and falls was observed in patients with urgency UI (OR, 1.76; 95% CI, 1.15–1.70) and those with stress UI (OR, 1.73; 95% CI, 1.39–2.15). Conclusions This meta-analysis, which was based on evidence from a review of the published literature, clearly demonstrated that UI is an important risk factor for falls in both general and older populations.
- Subjects :
- Male
Epidemiology
Urinary incontinence
Geriatric Depression
Database and Informatics Methods
Mathematical and Statistical Techniques
Elderly
Risk Factors
Medicine and Health Sciences
Database Searching
Geriatrics
Multidisciplinary
Depression
Statistics
Metaanalysis
Meta-analysis
Physical Sciences
Medicine
Female
medicine.symptom
Research Article
medicine.medical_specialty
Urology
Science
Geriatric Psychiatry
MEDLINE
Subgroup analysis
Research and Analysis Methods
Internal medicine
Mental Health and Psychiatry
medicine
Humans
Adults
Statistical Methods
Risk factor
Aged
Incontinence
Mood Disorders
business.industry
Odds ratio
Confidence interval
Urinary Incontinence
Age Groups
Medical Risk Factors
People and Places
Accidental Falls
Population Groupings
business
Mathematics
Subjects
Details
- ISSN :
- 19326203
- Volume :
- 16
- Database :
- OpenAIRE
- Journal :
- PLOS ONE
- Accession number :
- edsair.doi.dedup.....c8f601924f0b0826d2769e5ddd55ddcf