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Comparative In Vitro Activities of Caspofungin and Micafungin, Determined Using the Method of the European Committee on Antimicrobial Susceptibility Testing, against Yeast Isolates Obtained in France in 2005-2006

Authors :
Dorothée Raoux
Damien Hoinard
D. Moissenet
G. Galeazzi
I. Poilane
C. Lawrence
Françoise Dromer
Marie-Elisabeth Bougnoux
Olivier Lortholary
Eric Dannaoui
Unité de Parasitologie-Mycologie [CHU HEGP]
Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Européen Georges Pompidou [APHP] (HEGP)
Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)
Centre d'infectiologie Necker-Pasteur [CHU Necker]
Institut Pasteur [Paris] (IP)-CHU Necker - Enfants Malades [AP-HP]
Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)
Biologie et Pathogénicité fongiques (BPF)
Institut National de la Recherche Agronomique (INRA)-Institut Pasteur [Paris] (IP)
Service de Microbiologie Clinique [Paris]
CHU Necker - Enfants Malades [AP-HP]
Hôpital Louis Mourier - AP-HP [Colombes]
Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)
Laboratoire de microbiologie
Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Raymond Poincaré [AP-HP]
CHU Trousseau [APHP]
Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)
Université Pierre et Marie Curie - Paris 6 - UFR de Médecine Pierre et Marie Curie (UPMC)
Université Pierre et Marie Curie - Paris 6 (UPMC)
Centre National de Référence des Mycoses invasives et antifongiques - Mycologie moléculaire (CNRMA)
Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)
CHU Bordeaux [Bordeaux]
Source :
Antimicrobial Agents and Chemotherapy, Antimicrobial Agents and Chemotherapy, 2008, 52 (2), pp.778-781. ⟨10.1128/AAC.01140-07⟩
Publication Year :
2008
Publisher :
American Society for Microbiology, 2008.

Abstract

The in vitro activities of caspofungin and micafungin against 1,038 yeast isolates have been determined. The caspofungin and micafungin MICs were lower for Candida albicans , Candida glabrata , and Candida tropicalis than for Candida parapsilosis , Candida guilliermondii , and Candida krusei . A clear correlation was seen between the MICs for the two drugs.

Subjects

Subjects :
Antifungal Agents
Lipoproteins
[SDV]Life Sciences [q-bio]
Microbial Sensitivity Tests
Candida parapsilosis
Microbiology
Candida tropicalis
Echinocandins
Lipopeptides
chemistry.chemical_compound
Caspofungin
Drug Resistance, Fungal
Yeasts
Candida krusei
polycyclic compounds
medicine
Humans
Pharmacology (medical)
Candida albicans
Candida
Antibacterial agent
Pharmacology
biology
Candida glabrata
Micafungin
biochemical phenomena, metabolism, and nutrition
bacterial infections and mycoses
biology.organism_classification
stomatognathic diseases
Infectious Diseases
Mycoses
chemistry
Susceptibility
lipids (amino acids, peptides, and proteins)
France
medicine.drug

Details

ISSN :
10986596 and 00664804
Volume :
52
Database :
OpenAIRE
Journal :
Antimicrobial Agents and Chemotherapy
Accession number :
edsair.doi.dedup.....c8eee0cb3650ba3ea50bb69f22aaf0d6

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Authors Abstract Subjects Details