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Author Correction: Improved reference genome for the domestic horse increases assembly contiguity and composition

Authors :
Ian T. Fiddes
Carrie J. Finno
Michael S. DePriest
Alisa O. Vershinina
Jessica L. Petersen
Edward S. Rice
Richard E. Green
Rebecca R. Bellone
Douglas F. Antczak
Samantha A. Brooks
Nedda F. Saremi
Matthew S. Hestand
Ludovic Orlando
Brian P. Walenz
Theodore S. Kalbfleisch
Brendan O'Connell
James N. MacLeod
Molly E. McCue
Donald Miller
Joris Vermeesch
Ernest Bailey
Department of Population Health and Reproduction and the Veterinary Genetics Laboratory
University of California [Davis] (UC Davis)
University of California-University of California
College of Veterinary Medicine
University of Minnesota [Twin Cities] (UMN)
University of Minnesota System-University of Minnesota System
Section for GeoGenetics
Globe Institute
Faculty of Health and Medical Sciences
University of Copenhagen = Københavns Universitet (KU)-University of Copenhagen = Københavns Universitet (KU)-Faculty of Health and Medical Sciences
University of Copenhagen = Københavns Universitet (KU)-University of Copenhagen = Københavns Universitet (KU)
Department of Mathematics, University of Colorado
University of Colorado [Boulder]
Source :
Communications Biology, Communications Biology, Nature Publishing Group, 2019, 2 (1), ⟨10.1038/s42003-019-0591-3⟩, Communications Biology, Vol 2, Iss 1, Pp 1-1 (2019)
Publication Year :
2019
Publisher :
Springer Science and Business Media LLC, 2019.

Abstract

Recent advances in genomic sequencing technology and computational assembly methods have allowed scientists to improve reference genome assemblies in terms of contiguity and composition. EquCab2, a reference genome for the domestic horse, was released in 2007. Although of equal or better quality compared to other first-generation Sanger assemblies, it had many of the shortcomings common to them. In 2014, the equine genomics research community began a project to improve the reference sequence for the horse, building upon the solid foundation of EquCab2 and incorporating new short-read data, long-read data, and proximity ligation data. Here, we present EquCab3. The count of non-N bases in the incorporated chromosomes is improved from 2.33 Gb in EquCab2 to 2.41 Gb in EquCab3. Contiguity has also been improved nearly 40-fold with a contig N50 of 4.5 Mb and scaffold contiguity enhanced to where all but one of the 32 chromosomes is comprised of a single scaffold.

Details

ISSN :
23993642
Volume :
2
Database :
OpenAIRE
Journal :
Communications Biology
Accession number :
edsair.doi.dedup.....c8edbeaccbd5bd0533d568f62b22728b