Back to Search
Start Over
Author Correction: Improved reference genome for the domestic horse increases assembly contiguity and composition
- Source :
- Communications Biology, Communications Biology, Nature Publishing Group, 2019, 2 (1), ⟨10.1038/s42003-019-0591-3⟩, Communications Biology, Vol 2, Iss 1, Pp 1-1 (2019)
- Publication Year :
- 2019
- Publisher :
- Springer Science and Business Media LLC, 2019.
-
Abstract
- Recent advances in genomic sequencing technology and computational assembly methods have allowed scientists to improve reference genome assemblies in terms of contiguity and composition. EquCab2, a reference genome for the domestic horse, was released in 2007. Although of equal or better quality compared to other first-generation Sanger assemblies, it had many of the shortcomings common to them. In 2014, the equine genomics research community began a project to improve the reference sequence for the horse, building upon the solid foundation of EquCab2 and incorporating new short-read data, long-read data, and proximity ligation data. Here, we present EquCab3. The count of non-N bases in the incorporated chromosomes is improved from 2.33 Gb in EquCab2 to 2.41 Gb in EquCab3. Contiguity has also been improved nearly 40-fold with a contig N50 of 4.5 Mb and scaffold contiguity enhanced to where all but one of the 32 chromosomes is comprised of a single scaffold.
- Subjects :
- [SDV]Life Sciences [q-bio]
Contiguity
Medicine (miscellaneous)
Genome informatics
General Biochemistry, Genetics and Molecular Biology
03 medical and health sciences
0302 clinical medicine
Bellone
Author Correction
lcsh:QH301-705.5
Composition (language)
ComputingMilieux_MISCELLANEOUS
030304 developmental biology
[SDV.GEN]Life Sciences [q-bio]/Genetics
0303 health sciences
biology
Agriculture
Genomics
16. Peace & justice
biology.organism_classification
lcsh:Biology (General)
030220 oncology & carcinogenesis
Next-generation sequencing
General Agricultural and Biological Sciences
Humanities
Reference genome
Subjects
Details
- ISSN :
- 23993642
- Volume :
- 2
- Database :
- OpenAIRE
- Journal :
- Communications Biology
- Accession number :
- edsair.doi.dedup.....c8edbeaccbd5bd0533d568f62b22728b