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Potential oxidative stress in children with chronic constipation
- Source :
- World Journal of Gastroenterology. 11:368
- Publication Year :
- 2005
- Publisher :
- Baishideng Publishing Group Inc., 2005.
-
Abstract
- AIM To investigate the potential oxidative stress in children with chronic constipation and to explore its mechanisms. METHODS Seventy children with chronic constipation and 70 age- and sex-matched healthy children were enrolled in a randomized controlled study. Plasma levels of vitamins C and E, activities of superoxide dismutase and catalase and lipoperoxide level in erythrocytes were determined by spectrophotometry. RESULTS Compared with healthy children whose vitamin C, vitamin E, superoxide dismutase, catalase and lipoperoxide were 58.35+/-14.42 micromol/L, 27.15+/-6.55 micromol/L, 2 206+/-171 U/(g.Hb), 327.3+/-82.2 K/(g.Hb) and 19.18+/-4.27 nmol/(g.Hb) respectively, the levels of vitamin C, vitamin E, the activity of superoxide dismutase, and catalase in the children with chronic constipation significantly decreased [46.59+/-11.51 micromol/L, 20.65+/-4.80 micromol/L, 1943+/-147 U/(g.Hb) and 269.3+/-67.8 K/(g.Hb), respectively P
- Subjects :
- Male
Lipid Peroxides
medicine.medical_specialty
Erythrocytes
Adolescent
medicine.medical_treatment
Ascorbic Acid
medicine.disease_cause
Disease course
Superoxide dismutase
Clinical Research
Internal medicine
medicine
Humans
Vitamin E
Child
Chronic constipation
biology
Vitamin C
Superoxide Dismutase
business.industry
Gastroenterology
General Medicine
Plasma levels
Catalase
Oxidative Stress
Endocrinology
Case-Control Studies
Chronic Disease
biology.protein
Female
business
Constipation
Oxidative stress
Subjects
Details
- ISSN :
- 10079327
- Volume :
- 11
- Database :
- OpenAIRE
- Journal :
- World Journal of Gastroenterology
- Accession number :
- edsair.doi.dedup.....c8b1ba9a1ce4a3255061476b9a58b28b