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EROD activity and genotoxicity in the seabob shrimp Xiphopenaeus kroyeri exposed to benzo[a]pyrene (BaP) concentrations
- Source :
- Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual), Universidade de São Paulo (USP), instacron:USP
- Publication Year :
- 2011
-
Abstract
- Seabob shrimp Xiphopenaeus kroyeri is a marine species that lives in shallow waters of coastal environments, often impacted by polycyclic aromatic hydrocarbons (PAH) pollution. In the present study, seabob shrimp were exposed for 96 h to benzo[a]pyrene (BaP) at the nominal concentrations of 100, 200, 400 and 800 microg-L −1 . Animals of the control groups were exposed either to clean water or to the BaP-carrier (DMSO). At the end of the exposures, muscle tissues were sampled for BaP uptake assessment and hepatopancreas and hemolymph for EROD enzyme activity and hemocytes DNA damage, respectively. EROD activity and DNA damage increased significantly as a function of BaP exposure concentrations. Significant correlations between BaP uptake and both EROD activity and DNA damage suggest that they can be used as suitable tools for integrated levels of study on the biomarkers of PAH exposure.
- Subjects :
- animal structures
Health, Toxicology and Mutagenesis
Toxicology
medicine.disease_cause
complex mixtures
chemistry.chemical_compound
Penaeidae
Xiphopenaeus kroyeri
Hemolymph
polycyclic compounds
medicine
Benzo(a)pyrene
Cytochrome P-450 CYP1A1
Animals
Pharmacology
biology
Dose-Response Relationship, Drug
fungi
General Medicine
biology.organism_classification
Shrimp
TOXICOLOGIA
Comet assay
chemistry
Environmental chemistry
Pyrene
Hepatopancreas
Genotoxicity
Water Pollutants, Chemical
DNA Damage
Mutagens
Subjects
Details
- ISSN :
- 18727077
- Volume :
- 34
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Environmental toxicology and pharmacology
- Accession number :
- edsair.doi.dedup.....c89c585dfab88bb9f83a838189392413