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Comparison of micromorphometric testis tissue structures in antenatal fetuses and patients with congenital cryptorchidism
- Source :
- Andrologiâ i Genitalʹnaâ Hirurgiâ, Vol 16, Iss 2, Pp 27-36 (2015)
- Publication Year :
- 2015
- Publisher :
- ABV-press, 2015.
-
Abstract
- Investigation of paired organs, testicles in particular, in the antenatal period as compared to congenital cryptorchidism in the context of interrelationship can objectively approach the consideration of the whole set of physiological and pathological processes in them, by taking into account histophysiological identity. The paper gives the results of micromorphometric examinations of the units of a communication system (cellular populations) and the areas of parenchymatous and stromal structures (intertubular connective tissue, convoluted seminiferous tubules, and spermatogenic epithelium) in two groups: 1) 34 antenatal (ANT) fetuses at 20–41 weeks' gestation and 2) 46 children with congenital unilateral cryptorchidism (CR), in whom testis tissue biopsy specimens were examined at the age of 1 to 14 years. Determination of the similarity of micromorphometric structures (the number of cellular population in the intertubular connective tissue, convoluted seminiferous tubules, and the areas of intertubular connective tissue, spermatogenic epithelium, and capillary lumens) was analyzed to discover an identity in the testes tissues of the ANT fetuses versus the children with congenital unilateral CR, by considering the position and site of testicles. The findings indicate that there are synchronous changes of individual similar structures between the right and left testicle during its natural descent into the scrotum in the ANT fetuses and in the patients with congenital CR, which is suggestive of the symmetry and relationship between the contralateral sex glands in different ontogenetic groups. This may testify that there are similar processes occurring between the testis tissues in the children with congenital CR and in the ANT fetuses. The findings may become a ground for further consideration of congenital CR in the context of not only the micromorphometry, but also functional activity of tests tissue structures when comparatively analyzing these with the early stages of development of this organ, which will in the aggregate be able to look at this abnormality in another way.
- Subjects :
- Pathology
medicine.medical_specialty
Stromal cell
intertubular connective tissue
RD1-811
sertoli's cells
Urology
Population
Connective tissue
Context (language use)
Biology
Testicle
Unilateral cryptorchidism
communication systems
testicle
vascular bed area
antenatal period
Scrotum
Biopsy
medicine
education
education.field_of_study
medicine.diagnostic_test
Anatomy
spermatogenic epithelium
Diseases of the genitourinary system. Urology
medicine.anatomical_structure
Reproductive Medicine
cellular populations
Surgery
RC870-923
convoluted seminiferous tubules
cryptorchidism
morphometry
biopsy specimen
Subjects
Details
- Language :
- Russian
- ISSN :
- 20709781
- Volume :
- 16
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Andrologiâ i Genitalʹnaâ Hirurgiâ
- Accession number :
- edsair.doi.dedup.....c86adcd9efeed4716286d2d13855ab3f