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Carga y factores de riesgo para la neumonía adquirida en la comunidad de Pseudomonas aeruginosa : un estudio multinacional de prevalencia puntual de pacientes hospitalizados
- Source :
- Repositorio Universidad de la Sabana, Universidad de la Sabana, instacron:Universidad de la Sabana, Dipòsit Digital de la UB, Universidad de Barcelona, EUROPEAN RESPIRATORY JOURNAL, r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau, instname, Universidad de La Sabana, Intellectum Repositorio Universidad de La Sabana, Heitmann Bødtger, U C & GLIMP 2018, ' Burden and risk factors for Pseudomonas aeruginosa community-acquired pneumonia : a multinational point prevalence study of hospitalised patients ', European Respiratory Journal, vol. 52, no. 2, 1701190 . https://doi.org/10.1183/13993003.01190-2017, European Respiratory Journal, 52(2). EUROPEAN RESPIRATORY SOC JOURNALS LTD, Recercat. Dipósit de la Recerca de Catalunya
- Publication Year :
- 2018
-
Abstract
- Pseudomonas aeruginosa is a challenging bacterium to treat due to its intrinsic resistance to the antibiotics used most frequently in patients with community-acquired pneumonia (CAP). Data about the global burden and risk factors associated with P. aeruginosa-CAP are limited. We assessed the multinational burden and specific risk factors associated with P. aeruginosa-CAP. We enrolled 3193 patients in 54 countries with confirmed diagnosis of CAP who underwent microbiological testing at admission. Prevalence was calculated according to the identification of P. aeruginosa. Logistic regression analysis was used to identify risk factors for antibiotic-susceptible and antibiotic-resistant P. aeruginosa-CAP. The prevalence of P. aeruginosa and antibiotic-resistant P. aeruginosa-CAP was 4.2% and 2.0%, respectively. The rate of P. aeruginosa CAP in patients with prior infection/colonisation due to P. aeruginosa and at least one of the three independently associated chronic lung diseases (i.e. tracheostomy, bronchiectasis and/or very severe chronic obstructive pulmonary disease) was 67%. In contrast, the rate of P. aeruginosa-CAP was 2% in patients without prior P. aeruginosa infection/colonisation and none of the selected chronic lung diseases. The multinational prevalence of P. aeruginosa-CAP is low. The risk factors identified in this study may guide healthcare professionals in deciding empirical antibiotic coverage for CAP patients.
- Subjects :
- Pneumonia, Pseudomonas aeruginosa
Male
antibiotic resistance
Internationality
Cross-sectional study
bacterial colonization
very elderly
Prevalence
Drug Resistance
Drug resistance
Pneumònia adquirida a la comunitat
Pseudomonas aeruginosa community acquired pneumonia
Pulmonary Disease, Chronic Obstructive
0302 clinical medicine
Tracheostomy
Community-acquired pneumonia
Risk Factors
Epidemiology
80 and over
Medicine
Community-Acquired Infection
030212 general & internal medicine
Aged, 80 and over
Cross Infection
adult
article
Bacterial
Middle Aged
Antibiotic coverage
Bronchiectasis
Community-Acquired Infections
hospital patient
priority journal
risk factor
Aged
Cross-Sectional Studies
Drug Resistance, Bacterial
Female
Humans
Logistic Models
Pneumonia, Bacterial
Pseudomonas aeruginosa
Infectious diseases
Human
Pulmonary and Respiratory Medicine
medicine.medical_specialty
Chronic Obstructive
Logistic Model
Admission
Settore MED/10 - Malattie Dell'Apparato Respiratorio
chronic lung disease
Pulmonary Disease
03 medical and health sciences
Bronchiectasi
Internal medicine
Pseudomonas
controlled study
human
Cross-Sectional Studie
business.industry
Risk Factor
community acquired pneumonia
Pneumonia
medicine.disease
logistic regression analysis
major clinical study
antibiotic sensitivity
hospital admission
030228 respiratory system
microbiological examination
business
chronic obstructive lung disease
Subjects
Details
- Language :
- English
- ISSN :
- 09031936
- Database :
- OpenAIRE
- Journal :
- Repositorio Universidad de la Sabana, Universidad de la Sabana, instacron:Universidad de la Sabana, Dipòsit Digital de la UB, Universidad de Barcelona, EUROPEAN RESPIRATORY JOURNAL, r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau, instname, Universidad de La Sabana, Intellectum Repositorio Universidad de La Sabana, Heitmann Bødtger, U C & GLIMP 2018, ' Burden and risk factors for Pseudomonas aeruginosa community-acquired pneumonia : a multinational point prevalence study of hospitalised patients ', European Respiratory Journal, vol. 52, no. 2, 1701190 . https://doi.org/10.1183/13993003.01190-2017, European Respiratory Journal, 52(2). EUROPEAN RESPIRATORY SOC JOURNALS LTD, Recercat. Dipósit de la Recerca de Catalunya
- Accession number :
- edsair.doi.dedup.....c7f7bd6bcd70dc5f09754d6a223464ad