1582. Is Antibiotic Prophylaxis Needed for All Acute Variceal Bleeds in Decompensated Cirrhosis? A Retrospective Pilot Study

Background Guidelines recommend empiric antibiotic prophylaxis for acute variceal bleeding, but no studies compare the outcomes between those treated with guideline recommended duration and those not treated (low suspicion) or treatment duration truncated (negative work up). We hypothesized that outcomes may not be different between the two groups. Methods Retrospective pilot study for the period 2013–2017. Cases were extracted using ICD 9(4,560) and ICD 10(I8501, I8511) codes and the following criteria were applied. Inclusion: Age >18 years and decompensated cirrhosis with acute variceal bleeding. Exclusion: Age