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Human biologic monitoring based on blood donations to the National Blood Services
- Source :
- BMC Public Health, BMC Public Health, Vol 20, Iss 1, Pp 1-9 (2020)
- Publication Year :
- 2020
- Publisher :
- BioMed Central, 2020.
-
Abstract
- Background The ambient exposure does not always reflect the internal levels of pollution absorbed in the body. While human biomonitoring (HBM) could provide a valid estimate of exposure extent, it is usually an expensive and a heavily manpowered enterprise. Using samples collected during blood donations for HMB may provide a more efficient platform for a routine biomonitoring. Methods The current study is aimed to explore the feasibility of using the national blood banking system for the purposes of HBM, to compare between residents of a suspected polluted area in northern Israel (Haifa Bay) to the rest of the country. Specifically, we will assemble a geographically representative sample of blood donors residing in the study area and of the general population, to test for four industry and traffic-related metals: lead (Pb), cadmium (Cd), arsenic (As) and chromium (Cr). Samples of whole blood from donors will be tested in the Laboratory of Public Health Services managed by the Ministry of Health. The information on donors’ biomarkers levels will be further linked with the air pollution and meteorological data assessed at the location of the blood collection sites (short-term exposure) and donors’ permanent address (long-term exposure), as recorded by the monitoring stations spread throughout Israel and the satellite-based exposure models. The association between biomarkers and ambient environmental exposures will be assessed. The samples’ collection is planned for 2 years of 2020–2021. Discussion The information collected in this study could lead to environmental regulations within Haifa Bay area aimed to prevent exposure to high levels of hazardous chemicals.
- Subjects :
- Pollution
medicine.medical_specialty
media_common.quotation_subject
Population
Air pollution
Blood Donors
010501 environmental sciences
medicine.disease_cause
01 natural sciences
Hazardous Substances
03 medical and health sciences
Blood donations
Study Protocol
0302 clinical medicine
Environmental health
Air Pollution
Biomonitoring
Epidemiology
medicine
Humans
030212 general & internal medicine
Israel
education
0105 earth and related environmental sciences
media_common
education.field_of_study
business.industry
Public health
lcsh:Public aspects of medicine
Public Health, Environmental and Occupational Health
lcsh:RA1-1270
Environmental Exposure
Metals
Environmental Pollutants
Biostatistics
business
Biological Monitoring
Environmental Monitoring
Subjects
Details
- Language :
- English
- ISSN :
- 14712458
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- BMC Public Health
- Accession number :
- edsair.doi.dedup.....c7c84e57bb43ce48d1b4905d89f05267