Back to Search
Start Over
Prognostic value of cytokine and soluble Fcγ receptor assays in oncology
- Source :
- Immunology Letters. 44:145-148
- Publication Year :
- 1995
- Publisher :
- Elsevier BV, 1995.
-
Abstract
- The clinical course of a cancer is influenced by the interaction of tumour cells with the patient's immune system. It is thus conceivable that immunological parameters may be used as markers of prognostic or predictive value. We report here that increased serum levels of IL-6 is a signal of poor prognosis and predicts unresponsiveness to immunotherapy in patients with metastatic melanoma. In cervical cancer, IL-6 produced by infiltrating macrophages is a marker of invasive cancer. In patients with multiple myeloma, the plasmatic levels of soluble Fc gamma receptors are markers of the disease, sCD16 being drastically decreased and sCD32 being slightly increased.
- Subjects :
- Oncology
medicine.medical_specialty
medicine.medical_treatment
Immunology
Uterine Cervical Neoplasms
Immune system
Internal medicine
Humans
Immunology and Allergy
Medicine
Receptor
Interleukin 6
Melanoma
Multiple myeloma
biology
Interleukin-6
business.industry
Receptors, IgG
Cancer
Immunotherapy
Prognosis
medicine.disease
Testicular Hormones
Cytokine
biology.protein
Cytokines
Female
Multiple Myeloma
business
Subjects
Details
- ISSN :
- 01652478
- Volume :
- 44
- Database :
- OpenAIRE
- Journal :
- Immunology Letters
- Accession number :
- edsair.doi.dedup.....c7a9ef170c7fb3e20c8623938cc60b23