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A Chemoselective N-Arylation Reaction of 2-Aminopyridine Derivatives with Arynes

Authors :
Jianfei Zhao
Jian Wei
Xiaoguang Duan
Bin Cheng
Hongbin Zhai
Renqi Wang
Yun Li
Bing Zu
Taimin Wang
Source :
The Journal of organic chemistry. 82(18)
Publication Year :
2017

Abstract

A chemoselective N-arylation reaction of 2-aminopyridine derivatives with arynes in good to excellent yields has been described. The N-arylation products could be further applied to the facile construction of benzoisoquinuclidines and isoquinuclidines as well as pyrido[1,2-a]benzimidazoles.

Details

ISSN :
15206904
Volume :
82
Issue :
18
Database :
OpenAIRE
Journal :
The Journal of organic chemistry
Accession number :
edsair.doi.dedup.....c75e2cb5c6ea60fc4b881184dedacfcd