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A comparison of the in vivo neoendothelialization and wound healing processes of three atrial septal defect occluders used during childhood in a nonrandomized prospective trial
- Source :
- Anatolian Journal of Cardiology
- Publication Year :
- 2017
- Publisher :
- Kare Publishing, 2017.
-
Abstract
- Objective: We prospectively investigated the neoendothelialization of transcatheter secundum atrial septal defect (ASD) closure in children receiving one of three different occluders. Methods: Transcatheter ASD closure was performed for 44 children. The patients were divided into three groups: group I: Amplatzer, group II: Lifetech CeraFlex, and group III: Occlutech Figulla Flex II septal occluder. The data were prospectively analyzed. Markers of the three phases of wound healing were studied in all patients before and on the 1st and 10th days and 1st month post intervention. Results: The mean age of children was 7.08±3.51 years, and the mean weight was 26.07±15.07 kg. The mean ASD diameter was 12.65±3.50 mm. Groups I, II, and III comprised 34.1%, 31.8%, and 34.1% patients, respectively. No significant differences were observed between the groups regarding patient number, age, defect size, device diameter, or total septum/device ratio (p>0.05). Inflammatory and proliferative phase marker levels increased following the procedure (p0.05). Conclusion: All three devices were composed of nitinol with different surface coating techniques. Although the different manufacturing features were claimed to facilitate of neoendothelialization, no differences were observed among the three devices 1 month following the procedure.
- Subjects :
- Male
medicine.medical_specialty
Cardiac Catheterization
040301 veterinary sciences
Septal Occluder Device
Group ii
septal occluders
Septum secundum
030204 cardiovascular system & hematology
neoendothelialization
Heart Septal Defects, Atrial
Post-intervention
0403 veterinary science
03 medical and health sciences
secundum atrial septal defect
0302 clinical medicine
children
In vivo
Medicine
transcatheter closure
Humans
Septal Occluder
Prospective Studies
Child
Original Investigation
Wound Healing
business.industry
04 agricultural and veterinary sciences
Equipment Design
Surgery
Surface coating
Treatment Outcome
Prospective trial
Female
Cardiology and Cardiovascular Medicine
Wound healing
business
Subjects
Details
- Language :
- English
- ISSN :
- 21492271 and 21492263
- Volume :
- 18
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Anatolian Journal of Cardiology
- Accession number :
- edsair.doi.dedup.....c756c1ac90b8415e7423e4ea23ff10b1