A cost-effective fluorescence mini-microscope for biomedical applications

Authors :: Ting Wang
Šeila Selimović
Alessia Damilano
Nasim Annabi
Ali Khademhosseini
Shuichi Takayama
Akhtar Nadhman
Su Ryon Shin
Julio Aleman
Mehmet R. Dokmeci
Vijayan Manoharan
Sasha Cai Lesher-Perez
Yu Shrike Zhang
João Ribas
Source :: Lab on a chip, vol 15, iss 18, Zhang, YS; Ribas, J; Nadhman, A; Aleman, J; Selimovic, S; Lesher-Perez, SC; et al.(2015). A cost-effective fluorescence mini-microscope for biomedical applications. LAB ON A CHIP, 15(18), 3661-3669. doi: 10.1039/c5lc00666j. UCLA: Retrieved from: http://www.escholarship.org/uc/item/9bg6d0s9
Publication Year :: 2015
Publisher :: eScholarship, University of California, 2015.
Abstract: We have designed and fabricated a miniature microscope from off-the-shelf components and a webcam, with built-in fluorescence capability for biomedical applications. The mini-microscope was able to detect both biochemical parameters, such as cell/tissue viability (e.g. live/dead assay), and biophysical properties of the microenvironment such as oxygen levels in microfabricated tissues based on an oxygen-sensitive fluorescent dye. This mini-microscope has adjustable magnifications from 8-60×, achieves a resolution as high as

Database :: OpenAIRE
Journal :: Lab on a chip, vol 15, iss 18, Zhang, YS; Ribas, J; Nadhman, A; Aleman, J; Selimovic, S; Lesher-Perez, SC; et al.(2015). A cost-effective fluorescence mini-microscope for biomedical applications. LAB ON A CHIP, 15(18), 3661-3669. doi: 10.1039/c5lc00666j. UCLA: Retrieved from: http://www.escholarship.org/uc/item/9bg6d0s9
Accession number :: edsair.doi.dedup.....c708d9b312be2de8269beaf27a0da0b1
Full Text :: https://doi.org/10.1039/c5lc00666j.