Molecular models should not be published without the corresponding atomic coordinates

In PNAS, Romero et al. (1) present models of how glucocerebrosidase (GCase) interacts with saposin C (SAPC) and membranes. Unfortunately, the authors do not publish representative atomic coordinates or molecular dynamics trajectories for their models, denying researchers the opportunity to scrutinize the data Romero et al. (1) use to draw their functional conclusions. Access to these data is an important issue for structural biologists (2), and the open release of experimentally determined structural data has been the accepted practice for many years (3). Indeed, Romero et al. rely on several such publically available structures to carry out their study. Two specific issues with the Romero et al. (1) paper … [↵][1]1To whom correspondence should be addressed. Email: jed55{at}cam.ac.uk. [1]: #xref-corresp-1-1