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Multiscale modelling and diffraction-based characterization of elastic behaviour of human dentine
- Source :
- Acta Biomaterialia. 9(8):7937-7947
- Publication Year :
- 2013
- Publisher :
- Elsevier BV, 2013.
-
Abstract
- Human dentine is a hierarchical mineralized tissue with a two-level composite structure, with tubules being the prominent structural feature at a microlevel, and collagen fibres decorated with hydroxyapatite (HAp) crystallite platelets dominating the nanoscale. Few studies have focused on this two-level structure of human dentine, where the response to mechanical loading is thought to be affected not only by the tubule volume fraction at the microscale, but also by the shape and orientation distribution of mineral crystallites, and their nanoscale spatial arrangement and alignment. In this paper, in situ elastic strain evolution within HAp in dentine subjected to uniaxial compressive loading along both longitudinal and transverse directions was characterized simultaneously by two synchrotron X-ray scattering techniques: small- and wide-angle X-ray scattering (SAXS and WAXS, respectively). WAXS allows the evaluation of the apparent modulus linking the external load to the internal HAp crystallite strain, while the nanoscale HAp distribution and arrangement can be quantified by SAXS. We proposed an improved multiscale Eshelby inclusion model that takes into account the two-level hierarchical structure, and validated it with a multidirectional experimental strain evaluation. The agreement between the simulation and measurement indicates that the multiscale hierarchical model developed here accurately reflects the structural arrangement and mechanical response of human dentine. This study benefits the comprehensive understanding of the mechanical behaviour of hierarchical biomaterials. The knowledge of the mechanical properties related to the hierarchical structure is essential for the understanding and predicting the effects of structural alterations that may occur due to disease or treatment on the performance of dental tissues and their artificial replacements. © 2013 Acta Materialia Inc. Published by Elsevier Ltd.
- Subjects :
- Materials science
Compressive Strength
Biomedical Engineering
Modulus
Eshelby model
Mechanical properties
In Vitro Techniques
Models, Biological
Biochemistry
WAXS/SAXS
Biomaterials
X-Ray Diffraction
stomatognathic system
Hardness
Elastic Modulus
Tensile Strength
Humans
Computer Simulation
Composite material
Nanoscopic scale
Molecular Biology
Microscale chemistry
Small-angle X-ray scattering
Scattering
Dentine
General Medicine
Characterization (materials science)
Models, Chemical
Dentin
Volume fraction
Stress, Mechanical
Crystallite
Biotechnology
Subjects
Details
- ISSN :
- 17427061
- Volume :
- 9
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Acta Biomaterialia
- Accession number :
- edsair.doi.dedup.....c6eb59f0d86975ec154ba6197620e5d6
- Full Text :
- https://doi.org/10.1016/j.actbio.2013.04.020