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Necrotizing fasciitis caused by Mucor indicus in a pediatric bone marrow transplant recipient
- Source :
- Pediatric Transplantation. 22:e13294
- Publication Year :
- 2018
- Publisher :
- Wiley, 2018.
-
Abstract
- Necrotizing fasciitis is a life-threatening, rapidly progressing infection of fascia and subcutaneous cellular tissue typically caused by mixed aerobic and anaerobic bacteria. We present a case report of an immunocompromised 4-year-old female with necrotizing fasciitis from a rare fungal organism, Mucor indicus. The patient underwent multiple debridements and was treated for 10 months, first on liposomal amphotericin B (2 months) then posaconazole (8 months). Mucor indicus is a rarely described pathogen with only nine other cases described. Identification of this organism remains a challenge, and the need for further understanding of risk factors and organism susceptibility testing to help guide treatment is crucial.
- Subjects :
- 0301 basic medicine
Mucorales
Transplantation
Bone marrow transplant
Posaconazole
Pathology
medicine.medical_specialty
biology
business.industry
030106 microbiology
Fascia
biology.organism_classification
medicine.disease
Article
03 medical and health sciences
medicine.anatomical_structure
Mucor indicus
Pediatrics, Perinatology and Child Health
medicine
Anaerobic bacteria
Fasciitis
business
Pathogen
medicine.drug
Subjects
Details
- ISSN :
- 13973142
- Volume :
- 22
- Database :
- OpenAIRE
- Journal :
- Pediatric Transplantation
- Accession number :
- edsair.doi.dedup.....c6e84163d5ae16ad5207fa1094e663ed
- Full Text :
- https://doi.org/10.1111/petr.13294