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Necrotizing fasciitis caused by Mucor indicus in a pediatric bone marrow transplant recipient

Authors :
Mark D. Gonzalez
Ann E. Haight
Carlos Abramowsky
Inci Yildirim
Deborah Bloch
Source :
Pediatric Transplantation. 22:e13294
Publication Year :
2018
Publisher :
Wiley, 2018.

Abstract

Necrotizing fasciitis is a life-threatening, rapidly progressing infection of fascia and subcutaneous cellular tissue typically caused by mixed aerobic and anaerobic bacteria. We present a case report of an immunocompromised 4-year-old female with necrotizing fasciitis from a rare fungal organism, Mucor indicus. The patient underwent multiple debridements and was treated for 10 months, first on liposomal amphotericin B (2 months) then posaconazole (8 months). Mucor indicus is a rarely described pathogen with only nine other cases described. Identification of this organism remains a challenge, and the need for further understanding of risk factors and organism susceptibility testing to help guide treatment is crucial.

Details

ISSN :
13973142
Volume :
22
Database :
OpenAIRE
Journal :
Pediatric Transplantation
Accession number :
edsair.doi.dedup.....c6e84163d5ae16ad5207fa1094e663ed
Full Text :
https://doi.org/10.1111/petr.13294