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Supplemental Vitamins and Minerals for CVD Prevention and Treatment
- Source :
- Department of Medicine Publications
- Publication Year :
- 2018
- Publisher :
- Elsevier BV, 2018.
-
Abstract
- The authors identified individual randomized controlled trials from previous meta-analyses and additional searches, and then performed meta-analyses on cardiovascular disease outcomes and all-cause mortality. The authors assessed publications from 2012, both before and including the U.S. Preventive Service Task Force review. Their systematic reviews and meta-analyses showed generally moderate- or low-quality evidence for preventive benefits (folic acid for total cardiovascular disease, folic acid and B-vitamins for stroke), no effect (multivitamins, vitamins C, D, β-carotene, calcium, and selenium), or increased risk (antioxidant mixtures and niacin [with a statin] for all-cause mortality). Conclusive evidence for the benefit of any supplement across all dietary backgrounds (including deficiency and sufficiency) was not demonstrated; therefore, any benefits seen must be balanced against possible risks.
- Subjects :
- medicine.medical_specialty
Disease outcome
030204 cardiovascular system & hematology
law.invention
supplements
03 medical and health sciences
0302 clinical medicine
Randomized controlled trial
law
medicine
Humans
030212 general & internal medicine
Intensive care medicine
Randomized Controlled Trials as Topic
Cvd prevention
business.industry
Vitamins
Trace Elements
meta-analysis
Treatment Outcome
Cardiovascular Diseases
Meta-analysis
Dietary Supplements
all-cause mortality
Diet, Healthy
Cardiology and Cardiovascular Medicine
business
All cause mortality
Subjects
Details
- ISSN :
- 07351097
- Volume :
- 71
- Database :
- OpenAIRE
- Journal :
- Journal of the American College of Cardiology
- Accession number :
- edsair.doi.dedup.....c6e7ac824fc5c54c08d7f4d121b0ef84