DNA Nanostructures as Building Blocks for Molecular Biophysics and Future Therapeutics

Our group previously solved a key challenge for nanotechnology: programmable self-assembly of complex, three-dimensional nanostructures. Our solution was to build custom three-dimensional structures that can be conceived as stacks of nearly flat layers of DNA. I will discuss applications of this technology for molecular biophysics and therapeutics, including our efforts to build nanoscale capsules as delivery vehicles in vivo.