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Dendritic Cells Enhance Polyfunctionality of Adoptively Transferred T Cells That Target Cytomegalovirus in Glioblastoma
- Source :
- Cancer Research. 78:256-264
- Publication Year :
- 2018
- Publisher :
- American Association for Cancer Research (AACR), 2018.
-
Abstract
- Median survival for glioblastoma (GBM) remains Significance: A randomized pilot trial in patients with GBM implicates polyfunctional T-cell responses as a biomarker for effective antitumor immunotherapy. Cancer Res; 78(1); 256–64. ©2017 AACR.
- Subjects :
- Adult
Male
0301 basic medicine
Human cytomegalovirus
Cancer Research
Adoptive cell transfer
T-Lymphocytes
medicine.medical_treatment
Cytomegalovirus
CD8-Positive T-Lymphocytes
Immunotherapy, Adoptive
Article
Viral Matrix Proteins
03 medical and health sciences
Antigen
medicine
Humans
Aged
Brain Neoplasms
business.industry
virus diseases
Dendritic Cells
Immunotherapy
Middle Aged
Phosphoproteins
medicine.disease
Adoptive Transfer
Vaccination
Treatment Outcome
030104 developmental biology
Oncology
Immunology
Female
Tumor necrosis factor alpha
Glioblastoma
business
CD8
Ex vivo
Subjects
Details
- ISSN :
- 15387445 and 00085472
- Volume :
- 78
- Database :
- OpenAIRE
- Journal :
- Cancer Research
- Accession number :
- edsair.doi.dedup.....c6d26c35c2e1832b480f32a01d76b195
- Full Text :
- https://doi.org/10.1158/0008-5472.can-17-0469