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The prognostic value of cerebrospinal fluid characteristics in dogs without deep pain perception due to thoracolumbar disc herniation
- Source :
- Research in Veterinary Science. 100:189-196
- Publication Year :
- 2015
- Publisher :
- Elsevier BV, 2015.
-
Abstract
- Providing a pre-operative prognosis for dogs presented with absent deep pain perception (DPP) is extremely challenging, as the overall recovery rates widely vary. This study assesses the possible correlation between the severity of spinal cord injury and CSF cytology in 31 paraplegic dogs presented with absent DPP due to acute thoracolumbar intervertebral disc herniation (TL-IVDH). All dogs underwent surgical decompression immediately following diagnosis. CSF TNCC, macrophage percentage and macrophage to monocyte (MΦ:M) ratio were significantly higher in dogs that failed to regain DPP within 10 days post-operatively and in dogs that failed to regain ambulation at the end of the study period (P 0.05). MΦ:M of 0.73 and higher corresponded to a sensitivity of 54% and specificity of 100% for prediction of a negative long-term outcome. CSF TNCC, macrophage percentage and MΦ:M ratio effectively predicted regaining DPP and the long-term outcome in dogs that lost DPP due to acute TL-IVDH.
- Subjects :
- medicine.medical_specialty
Intervertebral Disc Degeneration
Lumbar vertebrae
Sensitivity and Specificity
Thoracic Vertebrae
Dogs
Cerebrospinal fluid
Predictive Value of Tests
medicine
Animals
Deep pain
Dog Diseases
Spinal cord injury
Spinal Cord Injuries
Cerebrospinal Fluid
Retrospective Studies
Lumbar Vertebrae
General Veterinary
business.industry
Retrospective cohort study
Prognosis
medicine.disease
Surgery
medicine.anatomical_structure
ROC Curve
Intervertebral Disc Displacement
Predictive value of tests
Thoracic vertebrae
business
Subjects
Details
- ISSN :
- 00345288
- Volume :
- 100
- Database :
- OpenAIRE
- Journal :
- Research in Veterinary Science
- Accession number :
- edsair.doi.dedup.....c6adecfac51e25935e15264193a3434b
- Full Text :
- https://doi.org/10.1016/j.rvsc.2015.03.017