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Relating calls to US poison centers for potential exposures to medications to Centers for Disease Control and Prevention reporting of influenza-like illness
- Source :
- Clinical toxicology (Philadelphia, Pa.). 54(3)
- Publication Year :
- 2016
-
Abstract
- The Centers for Disease Control (CDC) monitors influenza like illness (ILI) and the National Poison Data System (NPDS) warehouses call data uploaded by US poison centers regarding reported exposures to medication.We examined the relationship between calls to poison centers regarding reported exposures to medications commonly used to treat ILI and weekly reports of ILI.The CDC reports ILI, by age group, for each of 10 Health and Human Services (HHS) regions. We examined NPDS summary data from calls reported to poison centers regarding reported exposures to acetaminophen, cough/cold medications, and promethazine, for the same weeks, age groups, and HHS regions for influenza seasons 2000-2013. ILI and NPDS exposures were examined using graphical plots, descriptive statistics, stepwise regression analysis, and Geographic Information Systems (GIS).About 5,101,841 influenza-like illness cases were reported to the CDC, and 2,122,940 calls regarding reported exposures to medications commonly used to treat ILI, were reported by poison centers to the NPDS over the 13 flu seasons. Analysis of stepwise models of the linear untransformed data involving 24 NPDS data groups and for 60 ILI measures, over the 13 influenza seasons, demonstrated that reported exposures to medications used to treat ILI correlated with reported cases of ILI with a median R(2 )=( )0.489 (min R(2 )=( )0.248, max R(2 )=( )0.717), with mean ± SD of R(2 )=( )0.494 ± 0.121. Median number of parameters used (degrees of freedom - 1) was 7.NPDS data regarding poison center calls for selected ILI medication exposures were highly correlated with CDC ILI data. Since NPDS data are available in real time, it provides complimentary ILI monitoring. This approach may provide public health value in predicting other illnesses which are not currently as thoroughly monitored.
- Subjects :
- Gerontology
Adult
Male
medicine.medical_specialty
Antipyretics
Poison Control Centers
Adolescent
Drug-Related Side Effects and Adverse Reactions
Poison control
Toxicology
Suicide prevention
Occupational safety and health
03 medical and health sciences
Young Adult
0302 clinical medicine
Epidemiology
Injury prevention
Influenza, Human
medicine
Adverse Drug Reaction Reporting Systems
Humans
030212 general & internal medicine
Child
Acetaminophen
Aged
Retrospective Studies
Influenza-like illness
Analgesics
business.industry
Public health
Age Factors
Infant, Newborn
virus diseases
Infant
030208 emergency & critical care medicine
Retrospective cohort study
General Medicine
Analgesics, Non-Narcotic
Middle Aged
United States
respiratory tract diseases
Child, Preschool
Emergency medicine
Antiemetics
Female
Centers for Disease Control and Prevention, U.S
business
Subjects
Details
- ISSN :
- 15569519
- Volume :
- 54
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Clinical toxicology (Philadelphia, Pa.)
- Accession number :
- edsair.doi.dedup.....c67da80aac5c2fbc87e879f02a9f618a