Methylprednisolone for Heart Surgery in Infants — A Randomized, Controlled Trial

Authors :: Kevin D, Hill
Prince J, Kannankeril
Jeffrey P, Jacobs
H Scott, Baldwin
Marshall L, Jacobs
Sean M, O'Brien
David P, Bichel
Eric M, Graham
Brian, Blasiole
Ashraf, Resheidat
Adil S, Husain
S Ram, Kumar
Jerry L, Kirchner
Dianne S, Gallup
Joseph W, Turek
Mark, Bleiweis
Bret, Mettler
Alexis, Benscoter
Eric, Wald
Tara, Karamlou
Andrew H, Van Bergen
David, Overman
Pirooz, Eghtesady
Ryan, Butts
John S, Kim
John P, Scott
Brett R, Anderson
Michael F, Swartz
Patrick I, McConnell
David F, Vener
Jennifer S, Li
Kimberly, Teknipp
Source :: N Engl J Med
Publication Year :: 2022
Publisher :: Massachusetts Medical Society, 2022.
Abstract: BACKGROUND: Although perioperative prophylactic glucocorticoids have been used for decades, whether they improve outcomes in infants after heart surgery with cardiopulmonary bypass is unknown. METHODS: We conducted a multicenter, prospective, randomized, placebo-controlled, registry-based trial involving infants (

Subjects :: Humans
Insulin
Prospective Studies
General Medicine
Cardiac Surgical Procedures
Methylprednisolone
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