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Mother-to-infant vertical transmission of transfusion transmitted virus in South China
- Source :
- Journal of perinatal medicine. 32(5)
- Publication Year :
- 2004
-
Abstract
- A nested PCR was used to detect TTV DNA in serum from 490 mother-infant pairs to determine the rate of vertical transmission of TTV in Guangzhou City, P.R. China. TTV DNA was positive in 87 mothers and 12 of their babies, giving a prevalence of 17.8% in pregnant women and a mother-to-child transmission rate of 13.8%. In eight mother-infant pairs, TTV DNA nucleotide sequences from the mothers and their corresponding infants were identical. The homology of Guangzhou TTV and Japanese TTV ranged from 85.3%-98.2% at nucleotide level. TTV infection is common in pregnant women in South China and vertical transmission can occur. Guangzhou's and Japanese TTV isolates belong to the same genotype.
- Subjects :
- China
South china
Transmission rate
Molecular Sequence Data
Nucleotide level
Polymerase Chain Reaction
Virus
law.invention
Transfusion transmitted virus
law
Pregnancy
Genotype
Humans
Pregnancy Complications, Infectious
Polymerase chain reaction
DNA Primers
Torque teno virus
biology
Base Sequence
Infant, Newborn
Obstetrics and Gynecology
biology.organism_classification
Virology
DNA Virus Infections
Infectious Disease Transmission, Vertical
Pediatrics, Perinatology and Child Health
DNA, Viral
Female
Nested polymerase chain reaction
Subjects
Details
- ISSN :
- 03005577
- Volume :
- 32
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Journal of perinatal medicine
- Accession number :
- edsair.doi.dedup.....c62232d5acbd91bb0c8a5416eb700432