Serum vascular endothelial growth factor receptor-2 and adropin levels in age-related macular degeneration

Ornek, Nurgul/0000-0003-3068-1831 WOS: 000374276600013 PubMed: 27162728 AIM: To investigate the serum levels of vascular endothelial growth factor receptor-2 (VEGFR-2) and adropin in age-related macular degeneration (AMD) patients. METHODS: Ninety-eight AMD patients were included in the study. Seventy-eight age - and sex-matched healthy volunteers were recruited as the control group. Fundus florescein angiography and optical coherence tomography were performed to assess the posterior segment details. Serum VEGFR-2 and adropin levels were measured using enzyme-linked immunosorbent assays and compared between the study groups. RESULTS: AMD group had significantly increased fovea! retinal thickness, serum LDL and HDL levels and significantly decreased subfoveal choroidal thickness (P = 0.01, 0.047, 0.025 and