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Hot water extract of oriental melon leaf promotes hair growth and prolongs anagen hair cycle: In vivo and in vitro evaluation
- Source :
- Food Science and Biotechnology. 25:575-580
- Publication Year :
- 2016
- Publisher :
- Springer Science and Business Media LLC, 2016.
-
Abstract
- Effects of hot water extracts of oriental melon leaves (OML) on promotion of hair growth were investigated. Topical OML extract administration for hair regeneration was investigated using an in vivo model with C57BL/6 mice. Effects of OML extracts on the human hair growth were investigated using a hair follicle organ culture. OML extracts induced a shortened telogen to anagen conversion and promoted hair growth in the C57BL/6 mouse model. Culture of human hair follicles in the presence of OML extracts for 8 days promoted hair growth and prolonged the anagen duration due to induction of hair follicle cell proliferation in the bulb region. OML extracts exert a hair growth promotion effect and, therefore, can be used as a therapeutic agent for prevention of hair loss.
- Subjects :
- integumentary system
Biology
Hair follicle
Organ culture
medicine.disease
Applied Microbiology and Biotechnology
Article
Bulb
Andrology
030207 dermatology & venereal diseases
03 medical and health sciences
0302 clinical medicine
medicine.anatomical_structure
Hair loss
In vivo
Hair cycle
030220 oncology & carcinogenesis
Botany
otorhinolaryngologic diseases
medicine
Human hair growth
sense organs
Hair follicle cell proliferation
Food Science
Biotechnology
Subjects
Details
- ISSN :
- 20926456 and 12267708
- Volume :
- 25
- Database :
- OpenAIRE
- Journal :
- Food Science and Biotechnology
- Accession number :
- edsair.doi.dedup.....c5e663466f186d63bbed551bedc925e0