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Erectile dysfunction and sexual quality of life in patients who underwent low‐dose‐rate brachytherapy alone for prostate cancer
- Source :
- Andrologia. 54
- Publication Year :
- 2021
- Publisher :
- Hindawi Limited, 2021.
-
Abstract
- This study evaluated erectile function and sexual quality of life (QoL), and predictive factors for erectile dysfunction (ED) and the deterioration of sexual QoL in 70 patients who underwent low-dose-rate brachytherapy (LDR-BT) alone for prostate cancer without androgen deprivation therapy. Erectile function and sexual QoL were evaluated before and 1, 3, 6, 12, 24, 36, 48 and 60 months after LDR-BT. Binary logistic regression analysis was used to determine whether age, prostate volume, hypertension, diabetes, Brinkman's index, testosterone, baseline Sexual Health Inventory for Men (SHIM) score and post-implant dosimetry parameters could predict ED and deterioration of sexual QoL at 24 and 60 months after LDR-BT. After 24 and 60 months, ED was noted in 39 of 70 patients and 42 of 64 patients respectively. Furthermore, sexual QoL worsened in 42 of 70 and 43 of 64 patients respectively. Baseline SHIM score was identified as a significant predictor of ED (24 months: odds ratio [OR]: 0.83, p = 0.02; 60 months: OR: 0.83, p = 0.03) and the deterioration of sexual QoL (24 months: OR: 0.84, p = 0.03). LDR-BT for prostate cancer promoted decreased erectile function and sexual QoL, with high preimplant potency being a significant predictor of ED and the deterioration of sexual QoL.
- Subjects :
- Male
medicine.medical_specialty
Urology
medicine.medical_treatment
Brachytherapy
Androgen deprivation therapy
Prostate cancer
Endocrinology
Erectile Dysfunction
Quality of life
Internal medicine
medicine
Humans
business.industry
Shim (computing)
Prostatic Neoplasms
Androgen Antagonists
Testosterone (patch)
General Medicine
Odds ratio
medicine.disease
Erectile dysfunction
Child, Preschool
Quality of Life
business
Subjects
Details
- ISSN :
- 14390272 and 03034569
- Volume :
- 54
- Database :
- OpenAIRE
- Journal :
- Andrologia
- Accession number :
- edsair.doi.dedup.....c5ac054443af0d945c58f48c09c81908