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Utility of Preoperative Computed Tomography–Based Body Metrics in Relation to Postoperative Complications in Pediatric Liver Transplantation Recipients
- Source :
- Liver Transplantation. 27:1779-1787
- Publication Year :
- 2021
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2021.
-
Abstract
- Computed tomography (CT)-derived body metrics such as skeletal muscle index (SMI), psoas muscle index (PMI), and subcutaneous fat area index (ScFI) are measurable components of sarcopenia, frailty, and nutrition. While these body metrics are advocated in adults for predicting postoperative outcomes after liver transplantation (LT), little is known about their value in pediatric populations. This study assessed the relation between preoperative CT-based body metrics and postoperative short-term outcomes in pediatric LT recipients. Patients aged 0-18 years who underwent a primary LT were retrospectively included (n = 101; median age 0.5 years; range 0.2-17.1). SMI, PMI, and ScFI were derived from preoperative axial CT slices. Postoperative outcomes and complications within 90 days were correlated with the CT-based body metrics. To classify postoperative infections, the Clavien-Dindo (CD) classification was used. Subgroup analyses were performed for age groups ( 10 years old). An optimal threshold for test performance was defined using Youden's J-statistic and receiver operating characteristic curve as appropriate. ScFI was significantly (P = 0.001) correlated with moderate to severe postoperative infections (CD grade 3-5) in children aged
- Subjects :
- Adult
Sarcopenia
medicine.medical_specialty
Adolescent
medicine.medical_treatment
Computed tomography
Liver transplantation
Subcutaneous fat
law.invention
Postoperative Complications
Age groups
law
medicine
Humans
Child
Aged
Psoas Muscles
Retrospective Studies
Transplantation
Hepatology
medicine.diagnostic_test
Receiver operating characteristic
business.industry
Infant, Newborn
Infant
medicine.disease
Intensive care unit
Liver Transplantation
Surgery
Benchmarking
Child, Preschool
Tomography, X-Ray Computed
Risk assessment
business
Subjects
Details
- ISSN :
- 15276473 and 15276465
- Volume :
- 27
- Database :
- OpenAIRE
- Journal :
- Liver Transplantation
- Accession number :
- edsair.doi.dedup.....c5911e7b92c44e800606707787675413