Detection of Hepatitis B Virus DNA in Pancreas, Kidney and Skin of Two Human Carriers of the Virus

Authors :: Christian Bréchot
Pierre Tiollais
Anne Dejean
Serge Zafrani
Claire Lugassy
Recombinaison et expression génétique
Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
Service d'Anatomopathologie [Hôpital Henri Mondor - APHP]
CHU Henri Mondor
Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
Cheriet Rauline, Samia
CHU Henri Mondor [Créteil]
Source :: Journal of General Virology, Journal of General Virology, Microbiology Society, 1984, 65 (3), pp.651-655. ⟨10.1099/0022-1317-65-3-651⟩, Journal of General Virology, 1984, 65 (3), pp.651-655. ⟨10.1099/0022-1317-65-3-651⟩
Publication Year :: 1984
Publisher :: HAL CCSD, 1984.
Abstract: International audience; Using the Southern blot technique, we have analysed the presence and state of hepatitis B virus (HBV) DNA in non-hepatic tissue from two human HBV carriers. HBV DNA sequences were detected in the pancreas, kidney and skin, demonstrating HBV infection of these organs. Moreover, the restriction DNA patterns were consistent with the integration of these viral sequences into high molecular weight DNA. These results demonstrate that HBV infection is not restricted to the liver.

Language :: English
ISSN :: 00221317 and 14652099
Database :: OpenAIRE
Journal :: Journal of General Virology, Journal of General Virology, Microbiology Society, 1984, 65 (3), pp.651-655. ⟨10.1099/0022-1317-65-3-651⟩, Journal of General Virology, 1984, 65 (3), pp.651-655. ⟨10.1099/0022-1317-65-3-651⟩
Accession number :: edsair.doi.dedup.....c556848c9540382d992999eeb31dec6e
Full Text :: https://doi.org/10.1099/0022-1317-65-3-651⟩

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