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Energy intake and utilization vary during development in rats
- Source :
- ResearcherID
- Publication Year :
- 1999
-
Abstract
- Energy intake, utilization, and partitioning were determined in male Wistar rats from 25 to 180 d of age. Serum free triiodothyronine, leptin, and free fatty acid concentrations were also measured. Energy balance measurements allowed us to identify a period from 25 to 90 d, characterized by a rapid body growth rate and another from 90 to 180 d, during which body growth rate slowed. From 25 to 180 d, we found decreases in daily energy intake and expenditure, which were faster before 90 d. The first period was characterized by storage of lipid and protein. In the second period, protein deposition approached zero and the excess of ingested energy was entirely stored as fat, so that age-associated obesity began to develop. The inability of rats to maintain a stable body weight after the cessation of growth of lean body mass is not due to decreased resting metabolism but rather to a partial leptin resistance. J.
- Subjects :
- Leptin
Male
medicine.medical_specialty
Aging
Energy balance
Medicine (miscellaneous)
Growth
Biology
Fatty Acids, Nonesterified
Internal medicine
medicine
Animals
Rats, Wistar
chemistry.chemical_classification
Analysis of Variance
Nutrition and Dietetics
Triiodothyronine
Fatty acid
Proteins
Calorimetry, Indirect
Metabolism
medicine.disease
Obesity
Rats
Endocrinology
chemistry
Adipose Tissue
Basal metabolic rate
Lean body mass
Body Composition
Basal Metabolism
Energy Intake
Energy Metabolism
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- ResearcherID
- Accession number :
- edsair.doi.dedup.....c54b4e559e5c134de521ad5193d23442