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Hepatoid adenocarcinoma of the extrahepatic duct
- Publication Year :
- 2013
- Publisher :
- Baishideng Publishing Group Co., Limited, 2013.
-
Abstract
- Hepatoid carcinoma is a unique type of extrahepatic tumor associated with hepatic differentiation and displays the morphological and functional features of hepatocellular carcinoma. Hepatoid carcinoma of the extrahepatic duct has rarely been reported in the literature. We report a 62-year-old man who presented with epigastric discomfort, xanthochromia, dull pain of the right shoulder, nausea and pruitus. Microscopic examination of the extrahepatic duct indicated that the tumor was primarily composed of “hepatoid cells”, which were characterized by an eosinophilic cytoplasm, enlarged nucleus and prominent nucleoli. The cells were arranged in nests or proliferated in a trabecular pattern. Immunohistochemistry indicated that the tumor cells were positive for hepatocyte paraffin 1 and cytokeratins 8 and 18. Based on these findings, this case was diagnosed as hepatoid carcinoma of the extrahepatic duct.
- Subjects :
- Male
Pathology
medicine.medical_specialty
Cholangiopancreatography, Magnetic Resonance
Biopsy
Case Report
Bile Duct Neoplasm
Adenocarcinoma
Bile Ducts, Extrahepatic
Predictive Value of Tests
Trabecular Pattern
Eosinophilic
Biomarkers, Tumor
Medicine
Humans
medicine.diagnostic_test
business.industry
Gastroenterology
Cell Differentiation
General Medicine
Middle Aged
medicine.disease
Immunohistochemistry
medicine.anatomical_structure
Bile Duct Neoplasms
Hepatocellular carcinoma
Differential diagnosis
business
Duct (anatomy)
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....c52b6decae4ecf2a5030d3b9e8be2eb7