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Steroids, stress and the gut microbiome-brain axis
- Source :
- Journal of neuroendocrinology. 30(2)
- Publication Year :
- 2017
-
Abstract
- It is becoming well established that the gut microbiome has a profound impact on human health and disease. In this review, we explore how steroids can influence the gut microbiota and, in turn, how the gut microbiota can influence hormone levels. Within the context of the gut microbiome-brain axis, we discuss how perturbations in the gut microbiota can alter the stress axis and behaviour. In addition, human studies on the possible role of gut microbiota in depression and anxiety are examined. Finally, we present some of the challenges and important questions that need to be addressed by future research in this exciting new area at the intersection of steroids, stress, gut-brain axis and human health.
- Subjects :
- 0301 basic medicine
medicine.medical_specialty
steroid hormones
Endocrinology, Diabetes and Metabolism
Gut–brain axis
Context (language use)
androgen
Disease
Gut flora
Stress axis
digestive system
Article
stress
03 medical and health sciences
Cellular and Molecular Neuroscience
Human health
0302 clinical medicine
Endocrinology
Internal medicine
estrogen
microbiota
medicine
Animals
Humans
Gonadal Steroid Hormones
Human studies
biology
Endocrine and Autonomic Systems
digestive, oral, and skin physiology
Brain
biology.organism_classification
Gut microbiome
Gastrointestinal Microbiome
030104 developmental biology
030217 neurology & neurosurgery
Stress, Psychological
Subjects
Details
- ISSN :
- 13652826
- Volume :
- 30
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Journal of neuroendocrinology
- Accession number :
- edsair.doi.dedup.....c50d756f55eba09beebd8aa12d516260