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Successful Control of Dasatinib-related Chylothorax by the Japanese Herbal Medicine 'Goreisan'
- Source :
- Internal Medicine
- Publication Year :
- 2019
- Publisher :
- Japanese Society of Internal Medicine, 2019.
-
Abstract
- Dasatinib-related chylothorax is a rare adverse event, and the mechanism underlying its occurrence is still not fully understood. We herein report the case of a 73-year-old woman with chronic myeloid leukemia (CML) who developed dasatinib-related chylothorax refractory to conventional treatments, except for steroids. To the best of our knowledge, this is the first case of dasatinib-related chylothorax which was successfully controlled by combining diuretics with the Japanese herbal medicine “Goreisan.” “Goreisan” is known to inhibit aquaporin channels and regulate the water flow. Our findings showed that “Goreisan” is an effective treatment option for uncontrollable dasatinib-related chylothorax.
- Subjects :
- Adult
Male
medicine.medical_specialty
Water flow
Dasatinib
Antineoplastic Agents
Case Report
030204 cardiovascular system & hematology
Chylothorax
03 medical and health sciences
0302 clinical medicine
Refractory
chronic myeloid leukemia
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
hemic and lymphatic diseases
Internal Medicine
Humans
Medicine
Effective treatment
Goreisan
Intensive care medicine
Adverse effect
Aged
Aged, 80 and over
Plant Extracts
business.industry
Myeloid leukemia
General Medicine
Middle Aged
medicine.disease
Pleural Effusion
aquaporin
Female
Radiography, Thoracic
030211 gastroenterology & hepatology
Medicine, Kampo
business
Phytotherapy
medicine.drug
Subjects
Details
- ISSN :
- 13497235 and 09182918
- Volume :
- 58
- Database :
- OpenAIRE
- Journal :
- Internal Medicine
- Accession number :
- edsair.doi.dedup.....c50427c9570c09a68dd273f89e5c3424