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Insights into the genetic foundations of human communication
- Source :
- Neuropsychology Review, Neuropsychology Review, 25, 3-26, Neuropsychology Review, 25, 1, pp. 3-26
- Publication Year :
- 2014
-
Abstract
- The human capacity to acquire sophisticated language is unmatched in the animal kingdom. Despite the discontinuity in communicative abilities between humans and other primates, language is built on ancient genetic foundations, which are being illuminated by comparative genomics. The genetic architecture of the language faculty is also being uncovered by research into neurodevelopmental disorders that disrupt the normally effortless process of language acquisition. In this article, we discuss the strategies that researchers are using to reveal genetic factors contributing to communicative abilities, and review progress in identifying the relevant genes and genetic variants. The first gene directly implicated in a speech and language disorder was FOXP2. Using this gene as a case study, we illustrate how evidence from genetics, molecular cell biology, animal models and human neuroimaging has converged to build a picture of the role of FOXP2 in neurodevelopment, providing a framework for future endeavors to bridge the gaps between genes, brains and behavior.
- Subjects :
- Neuroinformatics
Comparative genomics
Cognitive science
Molecular cell biology
Language Disorders
Communication
Genetic variants
Brain
Genetic Variation
FOXP2
medicine.disease
Language acquisition
Language Development
Genetic architecture
Neuropsychology and Physiological Psychology
medicine
Animals
Humans
Language disorder
Psychology
Human communication
Cognitive psychology
Subjects
Details
- ISSN :
- 15736660 and 10407308
- Volume :
- 25
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Neuropsychology review
- Accession number :
- edsair.doi.dedup.....c500310b476e14b03f5439531d0c9f75