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Eosinophilic Gastroenteritis in an Ulcerative Colitis Patient During Treatment with Tumor Necrosis Factor-alpha Antagonist
- Source :
- Internal Medicine
- Publication Year :
- 2020
- Publisher :
- Japanese Society of Internal Medicine, 2020.
-
Abstract
- A 45-year-old man with steroid-dependent ulcerative pancolitis was hospitalized with frequent diarrhea, abdominal pain and distension 3 months after induction of golimumab, a tumor necrosis factor-alpha antagonist. Computed tomography showed wall thickening from the stomach to the colon and massive ascites. Peripheral blood test revealed eosinophilia. A large number of eosinophils were observed in the ascites fluid. Although esophagogastroduodenoscopy showed no abnormal findings and colonoscopy showed ulcerative colitis with a Mayo endoscopic subscore of 1, eosinophil infiltration was histologically observed. Based on these findings, we diagnosed him with eosinophilic gastroenteritis and started prednisolone. Consequently, his eosinophil counts and abdominal symptoms dramatically improved.
- Subjects :
- Male
eosinophilic gastroenteritis
Abdominal pain
medicine.medical_specialty
tumor necrosis factor-alpha antagonist
Prednisolone
Case Report
030204 cardiovascular system & hematology
Gastroenterology
ascites
03 medical and health sciences
Esophagus
0302 clinical medicine
Ileum
Internal medicine
Eosinophilia
Ascites
Internal Medicine
medicine
Eosinophilic gastroenteritis
Humans
Endoscopy, Digestive System
Glucocorticoids
ulcerative colitis
business.industry
Stomach
Rectum
Antibodies, Monoclonal
Colonoscopy
General Medicine
Middle Aged
Eosinophil
medicine.disease
Ulcerative colitis
Enteritis
Golimumab
Eosinophils
medicine.anatomical_structure
Gastritis
Colitis, Ulcerative
Tumor Necrosis Factor Inhibitors
030211 gastroenterology & hepatology
medicine.symptom
Tomography, X-Ray Computed
business
medicine.drug
Subjects
Details
- ISSN :
- 13497235 and 09182918
- Volume :
- 59
- Database :
- OpenAIRE
- Journal :
- Internal Medicine
- Accession number :
- edsair.doi.dedup.....c4bb5f22d4e02077940f7662ac1e2813